Endocrine Abstracts

Aim: In this study, we aimed to detect the serum Ghr levels in hypo and hyperthyroid patients at the time of diagnosis and after treatment in comparison with an age-, and sex-matched control group.Materials and methods: Thirty-two hypothyroid, 19 hyperthyroid and 30 control subjects were included in the study. Basal levels of serum free T3, free T4, TSH, anti-thyroid peroxidase (anti-TPO), anti Tg antibodies were measured by commercially available kits i...

Background: There is some evidence suggesting an interaction between renin-angiotensin-aldosterone system and parathyroid hormone (PTH). Decreased aldosterone levels after parathyroidectomy have been reported in patients with primary hyperparathyroidism (PHPT). Recently, most of the diagnosed patients with PHPT are mild or asymptomatic. Our aim was to investigate plasma aldosterone and renin concentrations in patients with asymptomatic PHPT.Methods: Thir...

Introduction: Hashimoto’s thyroiditis (HT) is common autoimmune thyroid disorder and is predominantly the clinical expression of cell-mediated immunity leading to destruction of thyroid cells. Vitamin D plays a role in the regulation of immunity and cell proliferation. So, do the serum levels of vitamin D reduced in HT?Methods: We examined the medical records of the ‘Thyroid policlinic’ patients with or without HT. Vitamin D, thyroid autoa...

Idiopathic granulomatous hypophysitis is a very rare inflammatory disease of the pituitary gland. Primary hypophysitis represents a difficult diagnostic challenge because it can imitate pituitary adenomas clinically and radiologically. The diagnosis is usually made histologically by hypophysectomy. We herein present a rare case of idiopathic granulomatous hypopysitis diagnosed primarily by pituitary biopsy.Case: A 50-year-old female patient presented wit...

Also cytopenies can be established in the evaluation of Graves’ disease (GD), isolated thrombocytopenia is very rare. Here, we present a case of immune thrombocytopenia incidentally found in the evaluation of GD. A 48-year-old female was admitted to our hospital with palpitation and anxiousness. The thyroid function tests were concordant with thyrotoxicosis. She had two subcentimetre nodules in the right thyroid lobe. Thyroid gland had increased iodine uptake. And thyroid...

A 67–year-old female patient was transferred to our hospital from a nursing home for high capillary glucose levels and foot ulcer considered as diabetic foot infection. Her past medical history could not be obtained because of mental retardation with unknown etiology and absence of relatives.A purulent foot ulcer sized 4×3 cm was found in right heel. She also had deformities in her hands, feet, and her nose. Peripheral neuropathy was also detec...

Introduction: Mutations on menin gene are associated with multiple endocrine neoplasia type 1.Case report: Thirty-five year-old male patient was admitted to our hospital with history of recurrent syncope episodes for 5 years which were attributed to hypoglycemia. In physical examination, he had obesity and multiple papillamatous skin lesions on his abdominal region. He had no family history of similar symptoms. His laboratory eveluation was consistent wi...

Background: There are plenty of primary genetic or secondary causes for both hypercholesterolemia and hypertriglyceridemia. Two different genetic causes in one patient does not generally come to mind in first place.Aim: We report a case who has two genetic alterations as a cause of hypercholesterolemia and hypertriglyceridemia.Case report: 62 year-old male referred because of high serum lipid levels. He had no active complaint. The...

Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia and characterized with autoantibodies to insulin in a patient without prior exposure to exogenous insulin. Medications with sulfydryl group and autoimmune diseases are known to be associated with this syndrome. Nearly 90% of the cases were reported in Japanese patients. We presented a Turkish patient with insülin autoimmune syndrome possibly caused by α-lipoic acid. A 62-year-old woman was admitted to ...

Objective: Thyroid incidentaloma is a common endocrinological disorder. Current literature regarding the risk of thyroid cancer in incidentalomas found in patients with non-thyroid cancer is limited. The aim of the present study was to investigate the frequency of thyroid malignancy in thyroid incidentalomas detected in patients with non-thyroid cancer.Methods: The database of 287 thyroid nodules from 161 patients with a history of non-thyroid cancer fol...